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Promethazine is a drug that’s used to treat a range of mental health issues, as well as allergies.

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How to take - Side Effects - Interactions - Things To Avoid - Pregnancy

It’s part of the class of drugs known as phenothiazines, which can treat a wide variety of conditions, including allergies and psychological issues.

Promethazine can be used as a sedative, and is commonly prescribed to minimise agitation, anxiety and restlessness, which can be brought on by a range of psychological conditions. It may also be used prior to surgery to help you feel relaxed and sleepy.

It’s also a powerful antiallergenic and can suppress the body’s reaction to histamine, which causes many of the symptoms associated with conditions like hay fever. Similarly, it can be used to prevent nausea and vomiting from occurring.

Promethazine works by suppressing the brain’s reaction to histamine, which your body’s immune system produces in response to injury, allergic reactions and inflammation. It’s also thought to act directly on several areas of the brain, leading to its sedative and anti-nausea effects.

If you’re suffering from any of the conditions discussed above and are looking for prescription medication and treatment – don’t delay. Speak to a doctor online now and start feeling better today.


How To Take Promethazine

Promethazine is typically prescribed in either tablet or liquid form and your doctor will provide instructions on how and how often to take the medication.

It’s typically taken orally (via your mouth) and is usually recommended to be taken before bed or prior to meal times.

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What Are The Side Effects of Promethazine?

Promethazine should never be given to young children, since it can cause severe breathing problems and even death.

Also, be sure to inform your doctor if you’re allergic to medications like thioridazine, fluphenazine and chlorpromazine – since a similar reaction may be caused by promethazine.

There’s a range of conditions that can put you at risk of an adverse reaction to the drug, including:

  • Asthma
  • Liver disease
  • Breathing disorders
  • Low calcium levels
  • Heart disease
  • High blood pressure
  • Seizures
  • If your immune system has been compromised and/or weakened.
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promethazine dosage

While promethazine can be used to treat several conditions, there are a range of potential side effects and you should contact a doctor immediately if you experience:

  • Severe drowsiness
  • Breathing problems
  • Confusion
  • Seizures
  • Heart palpitations
  • Twitches and other uncontrollable muscle movements

Other, less serious, side effects may include:

  • Blurred vision
  • Mild drowsiness
  • Dizzy spells
  • An excessively dry mouth
  • Insomnia
  • Feelings of anxiety
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Things To Avoid

Medical tests

If you’re undergoing medical tests for any conditions, be sure to inform the doctor that you’re taking promethazine, since it may influence the results.

Interactions with other drugs

A range of medications can have adverse interactions if taken at the same time as promethazine and may increase the chances of side effects.

Allergy medication, other types of sedatives, sleeping pills, muscle relaxants and medication used to treat seizures can all interact negatively with promethazine.

You should also be sure to tell your doctor if you’re currently taking medication.

Promethazine and Alcohol

You should avoid alcohol while you’re taking Promethazine.

You should not take promethazine alongside alcohol, since combining the two substances can make any feelings of drowsiness much worse.

Similarly, if you’re ill, alcohol can lengthen your recovery time, so it’s generally a good idea to steer clear of it until you feel better.

Is It Safe To Take Promethazine During Pregnancy?

Promethazine is sometimes prescribed for pregnant women suffering from hyperemesis gravidarum, a severe form of nausea and vomiting experienced during pregnancy.

However, it should not be taken in cases of milder nausea and vomiting, since the risks are not completely understood. Similarly, you should avoid taking promethazine when breast feeding.

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pregnancy and promethazine

How we can help

If you’re looking for more information on promethazine, or you’ve successfully used it to manage a condition in the past – speak to one of our GPs online today.

Our doctors can discuss your symptoms and advise whether promethazine would be the best way to treat your condition.

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